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Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules
Tubulin-targeting molecules are widely used cancer therapeutic agents. They inhibit microtubule-based structures, including the mitotic spindle, ultimately preventing cell division. The final fates of microtubule-inhibited cells are however often heterogeneous and difficult to predict. While recent...
Autores principales: | Cesare, Erica Di, Verrico, Annalisa, Miele, Andrea, Giubettini, Maria, Rovella, Paola, Coluccia, Antonio, Famiglini, Valeria, Regina, Giuseppe La, Cundari, Enrico, Silvestri, Romano, Lavia, Patrizia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386718/ https://www.ncbi.nlm.nih.gov/pubmed/28160569 http://dx.doi.org/10.18632/oncotarget.14980 |
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