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Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion

Cancer-associated fibroblasts (CAFs) play a central role in the complex process of tumor-stroma interaction and promote tumor growth. Emerging evidences also suggest that these fibroblasts are involved in the alteration of the anti-tumor immune response by impacting several immune cell populations,...

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Detalles Bibliográficos
Autores principales: Ziani, Linda, Safta-Saadoun, Thouraya Ben, Gourbeix, Johanne, Cavalcanti, Andrea, Robert, Caroline, Favre, Gilles, Chouaib, Salem, Thiery, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386721/
https://www.ncbi.nlm.nih.gov/pubmed/28423623
http://dx.doi.org/10.18632/oncotarget.15540