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Tumour-infiltrating regulatory T cell density before neoadjuvant chemoradiotherapy for rectal cancer does not predict treatment response

Neoadjuvant (preoperative) chemoradiotherapy (CRT) decreases the risk of rectal cancer recurrence and reduces tumour volume prior to surgery. However, response to CRT varies considerably between individuals and factors associated with response are poorly understood. Foxp3(+) regulatory T cells (Treg...

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Detalles Bibliográficos
Autores principales: McCoy, Melanie J., Hemmings, Chris, Anyaegbu, Chidozie C., Austin, Stephanie J., Lee-Pullen, Tracey F., Miller, Timothy J., Bulsara, Max K., Zeps, Nikolajs, Nowak, Anna K., Lake, Richard A., Platell, Cameron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386723/
https://www.ncbi.nlm.nih.gov/pubmed/28177891
http://dx.doi.org/10.18632/oncotarget.15048