PLCB4 copy gain and PLCß4 overexpression in primary gastrointestinal stromal tumors: Integrative characterization of a lipid-catabolizing enzyme associated with worse disease-free survival

To explore the implications of lipid catabolism-associated genes in gastrointestinal stromal tumors, we reappraised transcriptomic and genomic datasets and identified copy-gained and differentially upregulated PLCB4 gene associated with tumor progression. On full sections, PLCB4 mRNA abundance and P...

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Detalles Bibliográficos
Autores principales: Li, Chien-Feng, Liu, Ting-Ting, Chuang, I-Chieh, Chen, Yen-Yang, Fang, Fu-Min, Chan, Ti-Chun, Li, Wan-Shan, Huang, Hsuan-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386739/
https://www.ncbi.nlm.nih.gov/pubmed/28212550
http://dx.doi.org/10.18632/oncotarget.15306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386739/
https://www.ncbi.nlm.nih.gov/pubmed/28212550
http://dx.doi.org/10.18632/oncotarget.15306

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