Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer

BACKGROUND: Although loss of heterozygosity (LOH) at chromosome location 18q21 and decreased expression of SMAD4 in invasive colorectal cancers (CRCs) correlate with poor patient survival, the prognostic value of LOH at 18q21 and sub-cellular localization of SMAD4 have not been evaluated in relation...

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Detalles Bibliográficos
Autores principales: Jia, Xu, Shanmugam, Chandrakumar, Paluri, Ravi K., Jhala, Nirag C., Behring, Michael P., Katkoori, Venkat R., Sugandha, Shajan P., Bae, Sejong, Samuel, Temesgen, Manne, Upender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386755/
https://www.ncbi.nlm.nih.gov/pubmed/28423626
http://dx.doi.org/10.18632/oncotarget.15560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386755/
https://www.ncbi.nlm.nih.gov/pubmed/28423626
http://dx.doi.org/10.18632/oncotarget.15560

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