Cargando…

Prognostic value of loss of heterozygosity and sub-cellular localization of SMAD4 varies with tumor stage in colorectal cancer

BACKGROUND: Although loss of heterozygosity (LOH) at chromosome location 18q21 and decreased expression of SMAD4 in invasive colorectal cancers (CRCs) correlate with poor patient survival, the prognostic value of LOH at 18q21 and sub-cellular localization of SMAD4 have not been evaluated in relation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Xu, Shanmugam, Chandrakumar, Paluri, Ravi K., Jhala, Nirag C., Behring, Michael P., Katkoori, Venkat R., Sugandha, Shajan P., Bae, Sejong, Samuel, Temesgen, Manne, Upender
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386755/ https://www.ncbi.nlm.nih.gov/pubmed/28423626 http://dx.doi.org/10.18632/oncotarget.15560

Ejemplares similares

Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer
por: Shanmugam, Chandrakumar, et al.
Publicado: (2011)

Clinical Implications of Rabphillin-3A-Like Gene Alterations in Breast Cancer
por: Putcha, Balananda-Dhurjati Kumar, et al.
Publicado: (2015)

Comparison of Predicted Probabilities of Proportional Hazards Regression and Linear Discriminant Analysis Methods Using a Colorectal Cancer Molecular Biomarker Database
por: Meleth, Sreelatha, et al.
Publicado: (2007)

Prognostic Significance and Gene Expression Profiles of p53 Mutations in Microsatellite-Stable Stage III Colorectal Adenocarcinomas
por: Katkoori, Venkat R., et al.
Publicado: (2012)

Meta-analysis of the robustness of COVID-19 diagnostic kit performance during the early pandemic
por: Shanmugam, Chandrakumar, et al.
Publicado: (2022)

Immunophenotypic profiles and prognosis for colorectal mucinous adenocarcinomas are dependent on anatomic location
por: Patel, Chirag, et al.
Publicado: (2023)

Nef-M1, a CXCR4 Peptide Antagonist, Enhances Apoptosis and Inhibits Primary Tumor Growth and Metastasis in Breast Cancer
por: Bumpers, Harvey, et al.
Publicado: (2013)

The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype
por: Hebert-Magee, Shantel, et al.
Publicado: (2019)

Advances in pancreatic cancer biomarkers
por: Hasan, Syed, et al.
Publicado: (2019)

Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelial-to-mesenchymal transition in colon and breast cancers
por: Katkoori, Venkat R., et al.
Publicado: (2015)

DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer
por: Agarwal, Sumit, et al.
Publicado: (2022)

Functional consequence of the p53 codon 72 polymorphism in colorectal cancer
por: Katkoori, Venkat R., et al.
Publicado: (2017)

Role of chemoradiation in gallbladder cancer—a single institution retrospective analysis
por: Paluri, Ravi Kumar, et al.
Publicado: (2023)

Immunophenotype‐associated gene signature in ductal breast tumors varies by receptor subtype, but the expression of individual signature genes remains consistent
por: Behring, Michael, et al.
Publicado: (2021)

Serous fluid: Reactive conditions
por: Jhala, Nirag, et al.
Publicado: (2022)

Fine needle aspiration diagnosis of Rosai-Dorfman disease in an osteolytic lesion of bone
por: Li, Shaoying, et al.
Publicado: (2010)

The Chemokine CXCL8 in Carcinogenesis and Drug Response
por: Gales, Dominique, et al.
Publicado: (2013)

MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer()()
por: Agarwal, Sumit, et al.
Publicado: (2019)

Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells
por: Bedi, Deepa, et al.
Publicado: (2019)

Integrated landscape of copy number variation and RNA expression associated with nodal metastasis in invasive ductal breast carcinoma
por: Behring, Michael, et al.
Publicado: (2018)

Serous cavity metastasis: Evaluation of unknown primary
por: Jhala, Nirag, et al.
Publicado: (2022)

Predictive Value of MUC5AC Signature in Pancreatic Ductal Adenocarcinoma: A Hypothesis Based on Preclinical Evidence
por: Manne, Ashish, et al.
Publicado: (2023)

Obesity-Associated Myeloid-Derived Suppressor Cells Promote Apoptosis of Tumor-Infiltrating CD8 T Cells and Immunotherapy Resistance in Breast Cancer
por: Gibson, Justin T., et al.
Publicado: (2020)

Age-Dependent Heterogeneity of Lymph Node Metastases and Survival Identified by Analysis of a National Breast Cancer Registry
por: Behring, Michael, et al.
Publicado: (2022)

Diagnosis of metastatic fibrolamellar hepatocellular carcinoma by endoscopic ultrasound-guided fine needle aspiration
por: Crowe, Amanda, et al.
Publicado: (2011)

Disparities in Cervical Cancer Mortality Rates as Determined by the Longitudinal Hyperbolastic Mixed-Effects Type II Model
por: Tabatabai, Mohammad A., et al.
Publicado: (2014)

High-resolution CT, histopathologic, and clinical features of granulomatous pneumocystis jiroveci pneumonia
por: Dako, Farouk, et al.
Publicado: (2019)

Gain of function in somatic TP53 mutations is associated with immune‐rich breast tumors and changes in tumor‐associated macrophages
por: Behring, Michael, et al.
Publicado: (2019)

Hairy cell leukemia: A diagnosis by endoscopic ultrasound guided fine needle aspiration
por: Meara, Regina S, et al.
Publicado: (2006)

Therapeutic options for ampullary carcinomas. A review
por: Regalla, Dileep Kumar Reddy, et al.
Publicado: (2019)

Loss of Heterozygosity and Base Mutation Rates Vary Among Saccharomyces cerevisiae Hybrid Strains
por: Pankajam, Ajith V., et al.
Publicado: (2020)

Variable NF-κB pathway responses in colon cancer cells treated with chemotherapeutic drugs
por: Samuel, Temesgen, et al.
Publicado: (2014)

The Clinical Benefit of Adjuvant Therapy in Long-Term Survival of Early-Stage Ampullary Carcinoma: A Single Institutional Experience
por: Manne, Ashish, et al.
Publicado: (2020)

A Rare Multifocal Pattern of Type 2 Autoimmune Pancreatitis with Negative IgG4: A Potential Diagnostic Pitfall That May Mimic Multifocal Pancreatic Adenocarcinoma
por: Hota, Partha, et al.
Publicado: (2018)

First Observation of Compound Heterozygosity for Hb S/Hb Lepore-Hollandia in India
por: Mun, Amol, et al.
Publicado: (2021)

Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model()
por: Agarwal, Sumit, et al.
Publicado: (2020)

Corrigendum to ‘Targeting P4HA1 with a Small Molecule Inhibitor in a Colorectal Cancer PDX Model’ [Translational Oncology 13 (2020) 100754]
por: Agarwal, Sumit, et al.
Publicado: (2021)

Rapidly progressing lepidic pulmonary metastases from a treated poorly differentiated hepatocellular carcinoma demonstrating new pathologic features of cholangiocarcinoma: A potential diagnostic pitfall that may mimic pneumonia
por: Hota, Partha, et al.
Publicado: (2018)

A new method to detect loss of heterozygosity using cohort heterozygosity comparisons
por: Green, Michael R, et al.
Publicado: (2010)

Microbiome diversity in African American, European American, and Egyptian colorectal cancer patients
por: Elkholy, Amr, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kbegs8areqovej0in48n2jvejd