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Human Cell Assays for Synthesis-Dependent Strand Annealing and Crossing over During Double-Strand Break Repair
DNA double-strand breaks (DSBs) are one of the most deleterious types of lesions to the genome. Synthesis-dependent strand annealing (SDSA) is thought to be a major pathway of DSB repair, but direct tests of this model have only been conducted in budding yeast and Drosophila. To better understand th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Genetics Society of America
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386867/ https://www.ncbi.nlm.nih.gov/pubmed/28179392 http://dx.doi.org/10.1534/g3.116.037390 |