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Time-Variant Genetic Effects as a Cause for Preterm Birth: Insights from a Population of Maternal Cousins in Sweden

Preterm delivery (PTD) is the leading cause of neonatal mortality worldwide, yet its etiology remains largely unexplained. We propose that the genetic factors controlling this trait could act in a nonuniform manner during pregnancy, with each factor having a unique “window of sensitivity.” We test t...

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Detalles Bibliográficos
Autores principales: Juodakis, Julius, Bacelis, Jonas, Zhang, Ge, Muglia, Louis J., Jacobsson, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386882/
https://www.ncbi.nlm.nih.gov/pubmed/28250013
http://dx.doi.org/10.1534/g3.116.038612