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Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development

Tissue-specific transcription is critical for normal development, and abnormalities causing undesirable gene expression may lead to diseases such as cancer. Such highly organized transcription is controlled by enhancers with specific DNA sequences recognized by transcription factors. Enhancers are a...

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Detalles Bibliográficos
Autores principales: Ko, Je Yeong, Oh, Sumin, Yoo, Kyung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386954/
https://www.ncbi.nlm.nih.gov/pubmed/28359147
http://dx.doi.org/10.14348/molcells.2017.0033