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High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function

PURPOSE: PTEN is an important tumor suppressor in breast cancer. Here, we examined the prognostic and predictive value of PTEN and PTEN pseudogene (PTENP1) gene expression in patients with locally advanced breast cancer given neoadjuvant chemotherapy. METHODS: The association between pretreatment PT...

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Detalles Bibliográficos
Autores principales: Yndestad, Synnøve, Austreid, Eilin, Knappskog, Stian, Chrisanthar, Ranjan, Lilleng, Peer Kåre, Lønning, Per Eystein, Eikesdal, Hans Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387035/
https://www.ncbi.nlm.nih.gov/pubmed/28213783
http://dx.doi.org/10.1007/s10549-017-4160-5