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A Bioinformatics-Based Alternative mRNA Splicing Code that May Explain Some Disease Mutations Is Conserved in Animals

Deep sequencing of cDNAs made from spliced mRNAs indicates that most coding genes in many animals and plants have pre-mRNA transcripts that are alternatively spliced. In pre-mRNAs, in addition to invariant exons that are present in almost all mature mRNA products, there are at least 6 additional typ...

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Detalles Bibliográficos
Autores principales: Qu, Wen, Cingolani, Pablo, Zeeberg, Barry R., Ruden, Douglas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387049/
https://www.ncbi.nlm.nih.gov/pubmed/28443131
http://dx.doi.org/10.3389/fgene.2017.00038