Cargando…

Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses

Host immunity provides wide spectrum protection that serves to eradicate pathogens and cancer cells, while maintaining self-tolerance and immunological homeostasis. Ligation of the T cell receptor (TCR) by antigen activates signaling pathways that coordinately induce aerobic glycolysis, mitochondria...

Descripción completa

Detalles Bibliográficos
Autores principales: Patsoukis, Nikolaos, Weaver, Jessica D., Strauss, Laura, Herbel, Christoph, Seth, Pankaj, Boussiotis, Vassiliki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387055/
https://www.ncbi.nlm.nih.gov/pubmed/28443090
http://dx.doi.org/10.3389/fimmu.2017.00330