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Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses
Host immunity provides wide spectrum protection that serves to eradicate pathogens and cancer cells, while maintaining self-tolerance and immunological homeostasis. Ligation of the T cell receptor (TCR) by antigen activates signaling pathways that coordinately induce aerobic glycolysis, mitochondria...
Autores principales: | Patsoukis, Nikolaos, Weaver, Jessica D., Strauss, Laura, Herbel, Christoph, Seth, Pankaj, Boussiotis, Vassiliki A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387055/ https://www.ncbi.nlm.nih.gov/pubmed/28443090 http://dx.doi.org/10.3389/fimmu.2017.00330 |
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