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Japanese Encephalitis Virus Exploits Dopamine D2 Receptor-phospholipase C to Target Dopaminergic Human Neuronal Cells

Despite the availability of vaccines for Japanese encephalitis virus (JEV), the re-emerging virus remains a clinically important pathogen that causes acute encephalitis and permanent neuropsychiatric sequels. JEV highly targets dopaminergic neuron-rich brain regions including the thalamus and midbra...

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Detalles Bibliográficos
Autores principales: Simanjuntak, Yogy, Liang, Jian-Jong, Lee, Yi-Ling, Lin, Yi-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387065/
https://www.ncbi.nlm.nih.gov/pubmed/28443089
http://dx.doi.org/10.3389/fmicb.2017.00651