Inhibition of VEGF and Angiopoietin-2 to Reduce Brain Metastases of Breast Cancer Burden

For metastases in the central nervous system, angiogenesis enhances metastatic potential and promotes progression. Primary factors which drive vessel growth are vascular endothelial growth factor (VEGF) and angiopoietin-2. Preclinical models show inhibition of either factor reduces metastases spread...

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Detalles Bibliográficos
Autores principales: Bohn, Kaci A., Adkins, Chris E., Nounou, Mohamed I., Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387068/
https://www.ncbi.nlm.nih.gov/pubmed/28443023
http://dx.doi.org/10.3389/fphar.2017.00193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387068/
https://www.ncbi.nlm.nih.gov/pubmed/28443023
http://dx.doi.org/10.3389/fphar.2017.00193

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