Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes

IL-27, as a pleiotropic cytokine, promotes the differentiation of naïve T cells to Th1, while suppressing Th2 and Th17 differentiation in the periphery. However, the role of IL-27 in the thymocyte development remains unknown. Here we showed that IL-27 was highly expressed in thymic plasmacytoid dend...

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Detalles Bibliográficos
Autores principales: Tang, Hui, Zhang, Jie, Sun, Xiuyuan, Qian, Xiaoping, Zhang, Yu, Jin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387111/
https://www.ncbi.nlm.nih.gov/pubmed/27469302
http://dx.doi.org/10.1038/srep30448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387111/
https://www.ncbi.nlm.nih.gov/pubmed/27469302
http://dx.doi.org/10.1038/srep30448

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