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Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c‐Myc expression

c‐Myc overexpression has been implicated in several malignancies including gastric cancer. Here, we report that acidified bile acids enhance tumor progression and telomerase activity in gastric cancer via c‐Myc activation both in vivo and in vitro. c‐Myc mRNA and protein levels were assessed in ten...

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Detalles Bibliográficos
Autores principales: Wang, Xiaolong, Sun, Lei, Wang, Xijing, Kang, Huafeng, Ma, Xiaobin, Wang, Meng, Lin, Shuai, Liu, Meng, Dai, Cong, Dai, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387128/
https://www.ncbi.nlm.nih.gov/pubmed/28247570
http://dx.doi.org/10.1002/cam4.999