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oxLDL antibody inhibits MCP‐1 release in monocytes/macrophages by regulating Ca(2+)/K(+) channel flow

oxLDL peptide vaccine and its antibody adoptive transferring have shown a significantly preventive or therapeutic effect in atherosclerotic animal model. The molecular mechanism behind this is obscure. Here, we report that oxLDL induces MCP‐1 release in monocytes/macrophages through their TLR‐4 (Tol...

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Detalles Bibliográficos
Autores principales: Su, Jinyu, Zhou, Hui, Liu, Xianyan, Nilsson, Jan, Fredrikson, Gunilla Nordin, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387129/
https://www.ncbi.nlm.nih.gov/pubmed/27995732
http://dx.doi.org/10.1111/jcmm.13033