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Melanocortin receptor agonists MCR (1‐5) protect photoreceptors from high‐glucose damage and restore antioxidant enzymes in primary retinal cell culture

Retinal photoreceptors are particularly vulnerable to local high‐glucose concentrations. Oxidative stress is a risk factor for diabetic retinopathy development. Melanocortin receptors represent a family of G‐protein‐coupled receptors classified in five subtypes and are expressed in retina. Our previ...

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Detalles Bibliográficos
Autores principales: Maisto, Rosa, Gesualdo, Carlo, Trotta, Maria Consiglia, Grieco, Paolo, Testa, Francesco, Simonelli, Francesca, Barcia, Jorge Miquel, D'Amico, Michele, Di Filippo, Clara, Rossi, Settimio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387132/
https://www.ncbi.nlm.nih.gov/pubmed/27998021
http://dx.doi.org/10.1111/jcmm.13036