Cargando…

Melanocortin receptor agonists MCR (1‐5) protect photoreceptors from high‐glucose damage and restore antioxidant enzymes in primary retinal cell culture

Retinal photoreceptors are particularly vulnerable to local high‐glucose concentrations. Oxidative stress is a risk factor for diabetic retinopathy development. Melanocortin receptors represent a family of G‐protein‐coupled receptors classified in five subtypes and are expressed in retina. Our previ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Maisto, Rosa, Gesualdo, Carlo, Trotta, Maria Consiglia, Grieco, Paolo, Testa, Francesco, Simonelli, Francesca, Barcia, Jorge Miquel, D'Amico, Michele, Di Filippo, Clara, Rossi, Settimio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387132/ https://www.ncbi.nlm.nih.gov/pubmed/27998021 http://dx.doi.org/10.1111/jcmm.13036

Ejemplares similares

High Levels of Serum Ubiquitin and Proteasome in a Case of HLA-B27 Uveitis
por: Rossi, Settimio, et al.
Publicado: (2017)

Activation of Melanocortin Receptors MC(1) and MC(5) Attenuates Retinal Damage in Experimental Diabetic Retinopathy
por: Rossi, S., et al.
Publicado: (2016)

Corrigendum to “Activation of Melanocortin Receptors MC(1) and MC(5) Attenuates Retinal Damage in Experimental Diabetic Retinopathy”
por: Rossi, S., et al.
Publicado: (2021)

The Melanocortin MC5R as a New Target for Treatment of High Glucose-Induced Hypertrophy of the Cardiac H9c2 Cells
por: Trotta, Maria Consiglia, et al.
Publicado: (2018)

ARPE-19-derived VEGF-containing exosomes promote neovascularization in HUVEC: the role of the melanocortin receptor 5
por: Maisto, Rosa, et al.
Publicado: (2019)

Serum Iba-1, GLUT5, and TSPO in Patients With Diabetic Retinopathy: New Biomarkers for Early Retinal Neurovascular Alterations? A Pilot Study
por: Trotta, Maria Consiglia, et al.
Publicado: (2022)

Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose
por: Maisto, Rosa, et al.
Publicado: (2020)

Corrigendum: Resolvin D1 Modulates the Intracellular VEGF-Related miRNAs of Retinal Photoreceptors Challenged With High Glucose
por: Maisto, Rosa, et al.
Publicado: (2020)

Interplay between Intravitreal RvD1 and Local Endogenous Sirtuin-1 in the Protection from Endotoxin-Induced Uveitis in Rats
por: Rossi, S., et al.
Publicado: (2015)

Resolution of Inflammation in Retinal Disorders: Briefly the State
por: Trotta, Maria Consiglia, et al.
Publicado: (2022)

The Melanocortin System in Inflammatory Bowel Diseases: Insights into Its Mechanisms and Therapeutic Potentials
por: Gravina, Antonietta Gerarda, et al.
Publicado: (2023)

Stabilization of HIF-1α in Human Retinal Endothelial Cells Modulates Expression of miRNAs and Proangiogenic Growth Factors
por: Lazzara, Francesca, et al.
Publicado: (2020)

Effects of the Calix[4]arene Derivative Compound OTX008 on High Glucose-Stimulated ARPE-19 Cells: Focus on Galectin-1/TGF-β/EMT Pathway
por: Trotta, Maria Consiglia, et al.
Publicado: (2022)

Resolvin D1 Reduces the Immunoinflammatory Response of the Rat Eye following Uveitis
por: Settimio, Rossi, et al.
Publicado: (2012)

Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages
por: Rossi, S., et al.
Publicado: (2015)

Inhibition of Galectins and the P2X7 Purinergic Receptor as a Therapeutic Approach in the Neurovascular Inflammation of Diabetic Retinopathy
por: Lepre, Caterina Claudia, et al.
Publicado: (2023)

Systemic Beta-Hydroxybutyrate Affects BDNF and Autophagy into the Retina of Diabetic Mice
por: Trotta, Maria Consiglia, et al.
Publicado: (2022)

Fingolimod and Diabetic Retinopathy: A Drug Repurposing Study
por: Gesualdo, Carlo, et al.
Publicado: (2021)

Intraperitoneal Administration of Oxygen/Ozone to Rats Reduces the Pancreatic Damage Induced by Streptozotocin
por: Siniscalco, Dario, et al.
Publicado: (2018)

Oral Administration of Vitamin D3 Prevents Corneal Damage in a Knock-Out Mouse Model of Sjögren’s Syndrome
por: Trotta, Maria Consiglia, et al.
Publicado: (2023)

Autophagy: A Novel Pharmacological Target in Diabetic Retinopathy
por: Adornetto, Annagrazia, et al.
Publicado: (2021)

Corrigendum: Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate with Differences in the Expression of Selected Retinal miRNAs
por: Hermenean, Anca, et al.
Publicado: (2021)

Changes in Retinal Structure and Ultrastructure in the Aged Mice Correlate With Differences in the Expression of Selected Retinal miRNAs
por: Hermenean, Anca, et al.
Publicado: (2021)

Editorial: Chronic Inflammation and Neurodegeneration in Retinal Disease
por: Petrillo, Francesco, et al.
Publicado: (2021)

Inhibition of Ocular Aldose Reductase by a New Benzofuroxane Derivative Ameliorates Rat Endotoxic Uveitis
por: Di Filippo, C., et al.
Publicado: (2014)

Clinical and genetic features in Italian Bietti crystalline dystrophy patients
por: Rossi, Settimio, et al.
Publicado: (2013)

Family of melanocortin receptor (MCR) genes in mammals—mutations, polymorphisms and phenotypic effects
por: Switonski, M., et al.
Publicado: (2013)

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
por: Trotta, Maria Consiglia, et al.
Publicado: (2019)

Correlation Between Choriocapillaris Density and Retinal Sensitivity in Age-Related Macular Degeneration
por: Di Perna, Luigi, et al.
Publicado: (2021)

Sex and Age-Related Differences in Neuroinflammation and Apoptosis in Balb/c Mice Retina Involve Resolvin D1
por: Trotta, Maria Consiglia, et al.
Publicado: (2021)

The Importance of Melanocortin Receptors and Their Agonists in Pulmonary Disease
por: Moscowitz, Anna Elizabeth, et al.
Publicado: (2019)

Addition of the Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m to Prolonged and Moderate Exercise Training Enhanced Protection of the Rat Heart From Type-1 Diabetes
por: Ferraro, Bartolo, et al.
Publicado: (2019)

Bergmeister’s papilla in a young patient with type 1 sialidosis: case report
por: Rossi, Settimio, et al.
Publicado: (2020)

Hyperglycemia in Streptozotocin-Induced Diabetes Leads to Persistent Inflammation and Tissue Damage Following Uveitis Due to Reduced Levels of Ciliary Body Heme Oxygenase-1
por: Rossi, Settimio, et al.
Publicado: (2006)

Effects of Melanocortin 1 Receptor Agonists in Experimental Nephropathies
por: Lindskog Jonsson, Annika, et al.
Publicado: (2014)

Interactions of the Melanocortin-4 Receptor with the Peptide Agonist NDP-MSH
por: Chapman, Kathryn L., et al.
Publicado: (2010)

Resolvin D1 attenuates the inflammatory process in mouse model of LPS‐induced keratitis
por: Petrillo, Francesco, et al.
Publicado: (2020)

Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
por: Catania, A., et al.
Publicado: (2006)

Multimodal Assessment of the Prognostic Role of Ectopic Inner Foveal Layers on Epiretinal Membrane Surgery
por: Gesualdo, Carlo, et al.
Publicado: (2023)

Effects of the New Aldose Reductase Inhibitor Benzofuroxane Derivative BF-5m on High Glucose Induced Prolongation of Cardiac QT Interval and Increase of Coronary Perfusion Pressure
por: Di Filippo, C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_h078a5vesif3bg8pgcvu336t6n