The TGF‐β‐induced up‐regulation of NKG2DLs requires AKT/GSK‐3β‐mediated stabilization of SP1

Natural killer (NK) cells play an important role in preventing cancer development. NK group 2 member D (NKG2D) is an activating receptor expressed in the membrane of NK cells. Tumour cells expressing NKG2DL become susceptible to an immune‐dependent rejection mainly mediated by NK cells. The paradoxi...

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Detalles Bibliográficos
Autores principales: Chen, Xiao‐Hui, Lu, Lin‐lin, Ke, Hong‐Peng, Liu, Zong‐Cai, Wang, Hai‐Fang, Wei, Wei, Qi, Yi‐Fei, Wang, Hong‐Sheng, Cai, Shao‐Hui, Du, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387140/
https://www.ncbi.nlm.nih.gov/pubmed/28165192
http://dx.doi.org/10.1111/jcmm.13025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387140/
https://www.ncbi.nlm.nih.gov/pubmed/28165192
http://dx.doi.org/10.1111/jcmm.13025

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