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The TGF‐β‐induced up‐regulation of NKG2DLs requires AKT/GSK‐3β‐mediated stabilization of SP1
Natural killer (NK) cells play an important role in preventing cancer development. NK group 2 member D (NKG2D) is an activating receptor expressed in the membrane of NK cells. Tumour cells expressing NKG2DL become susceptible to an immune‐dependent rejection mainly mediated by NK cells. The paradoxi...
Autores principales: | Chen, Xiao‐Hui, Lu, Lin‐lin, Ke, Hong‐Peng, Liu, Zong‐Cai, Wang, Hai‐Fang, Wei, Wei, Qi, Yi‐Fei, Wang, Hong‐Sheng, Cai, Shao‐Hui, Du, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387140/ https://www.ncbi.nlm.nih.gov/pubmed/28165192 http://dx.doi.org/10.1111/jcmm.13025 |
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