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Inhibition of Orai1‐mediated Ca(2+) entry enhances chemosensitivity of HepG2 hepatocarcinoma cells to 5‐fluorouracil

Increasing evidence supports that activation of store‐operated Ca(2+) entry (SOCE) is implicated in the chemoresistance of cancer cells subjected to chemotherapy. However, the molecular mechanisms underlying chemoresistance are not well understood. In this study, we aim to investigate whether 5‐FU i...

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Detalles Bibliográficos
Autores principales: Tang, Bao‐Dong, Xia, Xin, Lv, Xiao‐Fei, Yu, Bei‐Xin, Yuan, Jia‐Ni, Mai, Xiao‐Yi, Shang, Jin‐Yan, Zhou, Jia‐Guo, Liang, Si‐Jia, Pang, Rui‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387165/
https://www.ncbi.nlm.nih.gov/pubmed/27878958
http://dx.doi.org/10.1111/jcmm.13029