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Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis

BACKGROUND: The recent findings of cancer-specific metabolic changes, including increased glucose and glutamine consumption, have provided new therapeutic targets for consideration. Fibroblast-like synoviocytes (FLS) from rheumatoid arthritis (RA) patients exhibit several tumor cell-like characteris...

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Detalles Bibliográficos
Autores principales: Takahashi, Soshi, Saegusa, Jun, Sendo, Sho, Okano, Takaichi, Akashi, Kengo, Irino, Yasuhiro, Morinobu, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387190/
https://www.ncbi.nlm.nih.gov/pubmed/28399896
http://dx.doi.org/10.1186/s13075-017-1283-3