Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cells

BACKGROUND: Itraconazole has been proved therapeutically effective against a variety of human cancers. This study assessed the effect of itraconazole on the Hedgehog (Hh) pathway and proliferation of human gastric cancer cells. METHODS: CCK-8 assay and colony formation assay were used to assess the...

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Detalles Bibliográficos
Autores principales: Hu, Qiang, Hou, Yi-Chao, Huang, Jiao, Fang, Jing-Yuan, Xiong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387201/
https://www.ncbi.nlm.nih.gov/pubmed/28399898
http://dx.doi.org/10.1186/s13046-017-0526-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387201/
https://www.ncbi.nlm.nih.gov/pubmed/28399898
http://dx.doi.org/10.1186/s13046-017-0526-0

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