Atorvastatin does not protect against ischemia-reperfusion damage in cholestatic rat livers

BACKGROUND: Extrahepatic cholestasis sensitizes the liver to ischemia/reperfusion (I/R) injury during surgery for perihilar cholangiocarcinoma. It is associated with pre-existent sterile inflammation, microvascular perfusion defects, and impaired energy status. Statins have been shown to protect aga...

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Detalles Bibliográficos
Autores principales: Wiggers, Jimme K., van Golen, Rowan F., Verheij, Joanne, Dekker, Annemiek M., van Gulik, Thomas M., Heger, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387220/
https://www.ncbi.nlm.nih.gov/pubmed/28399849
http://dx.doi.org/10.1186/s12893-017-0235-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387220/
https://www.ncbi.nlm.nih.gov/pubmed/28399849
http://dx.doi.org/10.1186/s12893-017-0235-9

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