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Meta-analysis approach as a gene selection method in class prediction: does it improve model performance? A case study in acute myeloid leukemia

BACKGROUND: Aggregating gene expression data across experiments via meta-analysis is expected to increase the precision of the effect estimates and to increase the statistical power to detect a certain fold change. This study evaluates the potential benefit of using a meta-analysis approach as a gen...

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Detalles Bibliográficos
Autores principales: Novianti, Putri W., Jong, Victor L., Roes, Kit C. B., Eijkemans, Marinus J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387259/
https://www.ncbi.nlm.nih.gov/pubmed/28399794
http://dx.doi.org/10.1186/s12859-017-1619-7