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Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats
BACKGROUND: Disturbances in coronary microcirculatory function, such as the endothelial glycocalyx, are early hallmarks in the development of obesity and insulin resistance. Accordingly, in the present study myocardial microcirculatory perfusion during rest and stress was assessed following metformi...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387275/ https://www.ncbi.nlm.nih.gov/pubmed/28399917 http://dx.doi.org/10.1186/s12933-017-0525-7 |