Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats

BACKGROUND: Disturbances in coronary microcirculatory function, such as the endothelial glycocalyx, are early hallmarks in the development of obesity and insulin resistance. Accordingly, in the present study myocardial microcirculatory perfusion during rest and stress was assessed following metformi...

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Detalles Bibliográficos
Autores principales: van Haare, Judith, Kooi, M. Eline, van Teeffelen, Jurgen W. G. E., Vink, Hans, Slenter, Jos, Cobelens, Hanneke, Strijkers, Gustav J., Koehn, Dennis, Post, Mark J., van Bilsen, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387275/
https://www.ncbi.nlm.nih.gov/pubmed/28399917
http://dx.doi.org/10.1186/s12933-017-0525-7

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