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Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice

BACKGROUND: The intratracheal instillation of bleomycin in mice induces early damage to alveolar epithelial cells and development of inflammation followed by fibrotic tissue changes and represents the most widely used model of pulmonary fibrosis to investigate human IPF. Histopathology is the gold s...

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Detalles Bibliográficos
Autores principales: Ruscitti, Francesca, Ravanetti, Francesca, Essers, Jeroen, Ridwan, Yanto, Belenkov, Sasha, Vos, Wim, Ferreira, Francisca, KleinJan, Alex, van Heijningen, Paula, Van Holsbeke, Cedric, Cacchioli, Antonio, Villetti, Gino, Stellari, Franco Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387277/
https://www.ncbi.nlm.nih.gov/pubmed/28400960
http://dx.doi.org/10.1186/s40248-017-0089-0