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Diversification of the kinetic properties of yeast NADP‐glutamate‐dehydrogenase isozymes proceeds independently of their evolutionary origin

In the yeast Saccharomyces cerevisiae, the ScGDH1 and ScGDH3 encoded glutamate dehydrogenases (NADP‐GDHs) catalyze the synthesis of glutamate from ammonium and α‐ketoglutarate (α‐KG). Previous kinetic characterization showed that these enzymes displayed different allosteric properties and respective...

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Detalles Bibliográficos
Autores principales: Campero‐Basaldua, Carlos, Quezada, Héctor, Riego‐Ruíz, Lina, Márquez, Dariel, Rojas, Erendira, González, James, El‐Hafidi, Mohammed, González, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387307/
https://www.ncbi.nlm.nih.gov/pubmed/27864882
http://dx.doi.org/10.1002/mbo3.419