The Rhodococcus equi virulence protein VapA disrupts endolysosome function and stimulates lysosome biogenesis

Rhodococcus equi (R. equi) is an important pulmonary pathogen in foals that often leads to the death of the horse. The bacterium harbors a virulence plasmid that encodes numerous virulence‐associated proteins (Vaps) including VapA that is essential for intracellular survival inside macrophages. Howe...

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Detalles Bibliográficos
Autores principales: Rofe, Adam P., Davis, Luther J., Whittingham, Jean L., Latimer‐Bowman, Elizabeth C., Wilkinson, Anthony J., Pryor, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387311/
https://www.ncbi.nlm.nih.gov/pubmed/27762083
http://dx.doi.org/10.1002/mbo3.416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387311/
https://www.ncbi.nlm.nih.gov/pubmed/27762083
http://dx.doi.org/10.1002/mbo3.416

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