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SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men

BACKGROUND: Sirtuin-6 (SIRT6) is involved in various crucial cellular pathways, being a key regulator of telomere structure, DNA repair, metabolism, transcriptional control and the NF-kappa B pathway. Sirt6 knock-out mice have been reported to develop typical features of aging and senescence at the...

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Detalles Bibliográficos
Autores principales: Hirvonen, Katariina, Laivuori, Hannele, Lahti, Jari, Strandberg, Timo, Eriksson, Johan G., Hackman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387321/
https://www.ncbi.nlm.nih.gov/pubmed/28399814
http://dx.doi.org/10.1186/s12881-017-0401-z