Cargando…
SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men
BACKGROUND: Sirtuin-6 (SIRT6) is involved in various crucial cellular pathways, being a key regulator of telomere structure, DNA repair, metabolism, transcriptional control and the NF-kappa B pathway. Sirt6 knock-out mice have been reported to develop typical features of aging and senescence at the...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387321/ https://www.ncbi.nlm.nih.gov/pubmed/28399814 http://dx.doi.org/10.1186/s12881-017-0401-z |