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Fetal testis organ culture reproduces the dynamics of epigenetic reprogramming in rat gonocytes

BACKGROUND: Epigenetic reprogramming is a critical step in male germ cell development that occurs during perinatal life. It is characterized by the remodeling of different epigenetic marks such as DNA methylation (5mC) and methylation of histone H3. It has been suggested that endocrine disruptors ca...

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Detalles Bibliográficos
Autores principales: Rwigemera, Arlette, Joao, Fabien, Delbes, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387332/
https://www.ncbi.nlm.nih.gov/pubmed/28413450
http://dx.doi.org/10.1186/s13072-017-0127-3