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Fetal testis organ culture reproduces the dynamics of epigenetic reprogramming in rat gonocytes
BACKGROUND: Epigenetic reprogramming is a critical step in male germ cell development that occurs during perinatal life. It is characterized by the remodeling of different epigenetic marks such as DNA methylation (5mC) and methylation of histone H3. It has been suggested that endocrine disruptors ca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387332/ https://www.ncbi.nlm.nih.gov/pubmed/28413450 http://dx.doi.org/10.1186/s13072-017-0127-3 |