Ku80 correlates with neoadjuvant chemotherapy resistance in human lung adenocarcinoma, but reduces cisplatin/pemetrexed-induced apoptosis in A549 cells

BACKGROUND: Ku80 is a DNA repair protein which involves in cell apoptosis and chemoresistance. However, it is unclear whether Ku80 correlates with the efficiency of neoadjuvant chemotherapy in human lung adenocarcinoma, and modulates cisplatin/pemetrexed-induced lung cancer cell apoptosis in vitro....

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Detalles Bibliográficos
Autores principales: Shang, Bin, Jia, Yang, Chen, Gang, Wang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387337/
https://www.ncbi.nlm.nih.gov/pubmed/28399858
http://dx.doi.org/10.1186/s12931-017-0545-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387337/
https://www.ncbi.nlm.nih.gov/pubmed/28399858
http://dx.doi.org/10.1186/s12931-017-0545-6

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