DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Recent technological advances have enabled DNA methylation to be assayed at single-cell resolution. However, current protocols are limited by incomplete CpG coverage and hence methods to predict missing methylation states are critical to enable genome-wide analyses. We report DeepCpG, a computationa...

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Detalles Bibliográficos
Autores principales: Angermueller, Christof, Lee, Heather J., Reik, Wolf, Stegle, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387360/
https://www.ncbi.nlm.nih.gov/pubmed/28395661
http://dx.doi.org/10.1186/s13059-017-1189-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387360/
https://www.ncbi.nlm.nih.gov/pubmed/28395661
http://dx.doi.org/10.1186/s13059-017-1189-z

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