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DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Recent technological advances have enabled DNA methylation to be assayed at single-cell resolution. However, current protocols are limited by incomplete CpG coverage and hence methods to predict missing methylation states are critical to enable genome-wide analyses. We report DeepCpG, a computationa...

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Detalles Bibliográficos
Autores principales:	Angermueller, Christof, Lee, Heather J., Reik, Wolf, Stegle, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387360/ https://www.ncbi.nlm.nih.gov/pubmed/28395661 http://dx.doi.org/10.1186/s13059-017-1189-z

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