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iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling

BACKGROUND: Epithelial–mesenchymal transition (EMT) and dysregulated microRNAs (miRNAs) have important roles in driving chemoresistance. We previously reported that iASPP is a key EMT inducer and could increase cisplatin resistance in cervical cancer (CC) cells. Herein, we investigate the downstream...

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Detalles Bibliográficos
Autores principales: Xiong, Ying, Sun, Fei, Dong, Peixin, Watari, Hidemichi, Yue, Junming, Yu, Min-fei, Lan, Chun-yan, Wang, Yin, Ma, Ze-biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387376/
https://www.ncbi.nlm.nih.gov/pubmed/28399926
http://dx.doi.org/10.1186/s13046-017-0520-6