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iASPP induces EMT and cisplatin resistance in human cervical cancer through miR-20a-FBXL5/BTG3 signaling
BACKGROUND: Epithelial–mesenchymal transition (EMT) and dysregulated microRNAs (miRNAs) have important roles in driving chemoresistance. We previously reported that iASPP is a key EMT inducer and could increase cisplatin resistance in cervical cancer (CC) cells. Herein, we investigate the downstream...
Autores principales: | Xiong, Ying, Sun, Fei, Dong, Peixin, Watari, Hidemichi, Yue, Junming, Yu, Min-fei, Lan, Chun-yan, Wang, Yin, Ma, Ze-biao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387376/ https://www.ncbi.nlm.nih.gov/pubmed/28399926 http://dx.doi.org/10.1186/s13046-017-0520-6 |
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