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Baseline JAK phosphorylation profile of peripheral blood leukocytes, studied by whole blood phosphospecific flow cytometry, is associated with 1-year treatment response in early rheumatoid arthritis

BACKGROUND: We found recently that baseline signal transducer and activator of transcription 3 phosphorylation in peripheral blood CD4(+) T cells of patients with early rheumatoid arthritis (RA) is associated with treatment response to synthetic disease-modifying antirheumatic drugs (DMARDs). This p...

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Detalles Bibliográficos
Autores principales: Kuuliala, Krista, Kuuliala, Antti, Koivuniemi, Riitta, Kautiainen, Hannu, Repo, Heikki, Leirisalo-Repo, Marjatta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387378/
https://www.ncbi.nlm.nih.gov/pubmed/28399940
http://dx.doi.org/10.1186/s13075-017-1278-0