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Citrate shows protective effects on cardiovascular and renal function in ischemia-induced acute kidney injury
BACKGROUND: Ischemia and reperfusion (I/R) is one of the major causes of acute kidney injury (AKI). Citrate reduces hypoxia-induced mitochondrial energetic deficits in isolated proximal tubules. Moreover, citrate anticoagulation is now frequently used in renal replacement therapy. In the present stu...
Autores principales: | Bienholz, Anja, Reis, Jonas, Sanli, Pinar, de Groot, Herbert, Petrat, Frank, Guberina, Hana, Wilde, Benjamin, Witzke, Oliver, Saner, Fuat H., Kribben, Andreas, Weinberg, Joel M., Feldkamp, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387390/ https://www.ncbi.nlm.nih.gov/pubmed/28395656 http://dx.doi.org/10.1186/s12882-017-0546-1 |
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