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Bitter Taste Receptor Agonists Mitigate Features of Allergic Asthma in Mice

Asthma is characterized by airway inflammation, mucus secretion, remodeling and hyperresponsiveness (AHR). Recent research has established the bronchodilatory effect of bitter taste receptor (TAS2R) agonists in various models. Comprehensive pre-clinical studies aimed at establishing effectiveness of...

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Detalles Bibliográficos
Autores principales: Sharma, Pawan, Yi, Roslyn, Nayak, Ajay P., Wang, Nadan, Tang, Francesca, Knight, Morgan J., Pan, Shi, Oliver, Brian, Deshpande, Deepak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387415/
https://www.ncbi.nlm.nih.gov/pubmed/28397820
http://dx.doi.org/10.1038/srep46166