Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

Aging is a major international concern that brings formidable socioeconomic and healthcare challenges. Small molecules capable of improving the health of older individuals are being explored. Small molecules that enhance cellular stress resistance are a promising avenue to alleviate declines seen in...

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Detalles Bibliográficos
Autores principales: Fang, Evandro F., Waltz, Tyler B., Kassahun, Henok, Lu, Qiping, Kerr, Jesse S., Morevati, Marya, Fivenson, Elayne M., Wollman, Bradley N., Marosi, Krisztina, Wilson, Mark A., Iser, Wendy B., Eckley, D. Mark, Zhang, Yongqing, Lehrmann, Elin, Goldberg, Ilya G., Scheibye-Knudsen, Morten, Mattson, Mark P., Nilsen, Hilde, Bohr, Vilhelm A., Becker, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387417/
https://www.ncbi.nlm.nih.gov/pubmed/28397803
http://dx.doi.org/10.1038/srep46208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387417/
https://www.ncbi.nlm.nih.gov/pubmed/28397803
http://dx.doi.org/10.1038/srep46208

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