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Structure of the Ebola virus glycoprotein spike within the virion envelope at 11 Å resolution

We present the structure of the surface Ebola virus (EBOV) trimeric glycoprotein (GP) spike at 11 Å resolution, in situ within the viral plasma membrane of purified virus particles. GP functions in cellular attachment, endosomal entry, and membrane fusion to initiate infection, and is a key therapeu...

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Detalles Bibliográficos
Autores principales: Beniac, Daniel R., Booth, Timothy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387728/
https://www.ncbi.nlm.nih.gov/pubmed/28397863
http://dx.doi.org/10.1038/srep46374