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The structure of Lactococcus lactis thioredoxin reductase reveals molecular features of photo-oxidative damage

The NADPH-dependent homodimeric flavoenzyme thioredoxin reductase (TrxR) provides reducing equivalents to thioredoxin, a key regulator of various cellular redox processes. Crystal structures of photo-inactivated thioredoxin reductase (TrxR) from the Gram-positive bacterium Lactococcus lactis have be...

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Detalles Bibliográficos
Autores principales: Skjoldager, Nicklas, Blanner Bang, Maria, Rykær, Martin, Björnberg, Olof, Davies, Michael J., Svensson, Birte, Harris, Pernille, Hägglund, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387739/
https://www.ncbi.nlm.nih.gov/pubmed/28397795
http://dx.doi.org/10.1038/srep46282