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Feasibility of melatonin for prevention of delirium in critically ill patients: a protocol for a multicentre, randomised, placebo-controlled study

INTRODUCTION: Delirium is highly prevalent in the intensive care unit (ICU) and is associated with adverse clinical outcomes. At this time, there is no drug that effectively prevents delirium in critically ill patients. Alterations in melatonin secretion and metabolism may contribute to the developm...

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Detalles Bibliográficos
Autores principales: Burry, Lisa, Scales, Damon, Williamson, David, Foster, Jennifer, Mehta, Sangeeta, Guenette, Melanie, Fan, Eddy, Detsky, Michael, Azad, Azar, Bernard, Francis, Rose, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387939/
https://www.ncbi.nlm.nih.gov/pubmed/28363933
http://dx.doi.org/10.1136/bmjopen-2016-015420