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Anticancer Dose Adjustment for Patients with Renal and Hepatic Dysfunction: From Scientific Evidence to Clinical Application

Most anticancer agents exhibit a narrow therapeutic index, i.e., a small change in plasma concentrations can lead to a less efficacious treatment or an unacceptable degree of toxicity. This study aimed at providing health professionals with a feasible and time-saving tool to adapt the dose of antica...

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Detalles Bibliográficos
Autores principales: Hendrayana, Tomi, Wilmer, André, Kurth, Verena, Schmidt-Wolf, Ingo GH, Jaehde, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388145/
https://www.ncbi.nlm.nih.gov/pubmed/28264440
http://dx.doi.org/10.3390/scipharm85010008