SL2B aptamer and folic acid dual-targeting DNA nanostructures for synergic biological effect with chemotherapy to combat colorectal cancer

DNA nanostructures prepared by self-assembly possess good stability, high biocompatibility, and low immunogenicity as drug delivery vehicles. In this work, DNA tetrahedron (TD) was constructed and modified with SL2B aptamer (S) and folic acid (F). TD possessed a small diameter (~6 nm) and entered in...

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Detalles Bibliográficos
Autores principales: Sun, Pengchao, Zhang, Nan, Tang, Yafang, Yang, Yanan, Chu, Xiao, Zhao, Yongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388264/
https://www.ncbi.nlm.nih.gov/pubmed/28435250
http://dx.doi.org/10.2147/IJN.S132929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388264/
https://www.ncbi.nlm.nih.gov/pubmed/28435250
http://dx.doi.org/10.2147/IJN.S132929

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