Cargando…

A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron

Genomic imprinting is an epigenetic regulation that leads to gene expression in a parent-of-origin specific manner. AFF3, the central component of the Super Elongation Complex-like 3 (SEC-L3), is enriched at both the intergenic-differentially methylated region (IG-DMR) and the Meg3 enhancer within t...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yan, Shen, Yang, Dai, Qian, Yang, Qian, Zhang, Yue, Wang, Xin, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388394/
https://www.ncbi.nlm.nih.gov/pubmed/28180295
http://dx.doi.org/10.1093/nar/gkw1051