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A permissive chromatin state regulated by ZFP281-AFF3 in controlling the imprinted Meg3 polycistron
Genomic imprinting is an epigenetic regulation that leads to gene expression in a parent-of-origin specific manner. AFF3, the central component of the Super Elongation Complex-like 3 (SEC-L3), is enriched at both the intergenic-differentially methylated region (IG-DMR) and the Meg3 enhancer within t...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388394/ https://www.ncbi.nlm.nih.gov/pubmed/28180295 http://dx.doi.org/10.1093/nar/gkw1051 |